ntfs is the Windows file system, which can cause problems on linux. I recommend downloading the game again to an ext4 partition, which is compatible with both windows and linux. For me, practically all games work with proton experimental.
Step-by-step guide:
- Back up the ntfs partition
- Convert the ntfs partition into ext4 (you can use GParted)
- Download Bottles
- Follow this simple tutorial: https://youtu.be/gme5RSvq8Nc
- enjoy


Have you tried running Heroic from the terminal? Do you get any error messages?