Topical application of caffeine:
caffeine, which is known to have antioxidant properties, impedes keratinocyte proliferation and migration, suggesting that it may have an inhibitory effect on wound healing and epithelialisation.
Daily consumption of caffeine impairs graft viability when given in medium dose and increases collagen synthesis, irrespective of dosage. This study was in experimental rats; the results are not directly translatable to humans.
On the topic of collagen synthesis, I decided to find a study about it, not to leave the topic unfinished, here’s what I found:
Caffeine reduces collagen synthesis in human cultured skin fibroblasts.
Based on all my findings, I would personally suggest avoiding caffeine altogether if you’ve a healing wound.
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